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Kawahara, T., Quinn, M

Orthogonal therapies Two therapies are considered orthogonal if they target a cancer in two different ways such that a resistance mechanism for the first therapy is unlikely to suppress the activity of the second therapy and vice versa

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Curr Opin BioMed Eng

The ethanol group exhibited a significant reduction in the mRNA levels and protein expression of ZO-1, Claudin-1, and Occludin compared to the control group