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Over time, this can help skin look smoother, more refined, and more even in tone

GPx-4 plays a crucial role in cellular defense against oxidative stress, primarily by reducing lipid hydroperoxides to their corresponding alcohols and converting free hydrogen peroxide into water, thereby preventing lipid peroxidation of cell membranes

Key scientific concepts Given its important role in cell metabolism, the ability to monitor and model the glutamine metabolic pathways are highlighted

Acknowledgements The authors acknowledge Figdraw for assistance with figure creation

Further, anticonvulsive drugs (e.g., Phenytoin) or hyperosmotic (e.g., Dexamethasone) therapy may be added to CaNa 2 EDTA infusion if needed