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In the present study, we investigated the protective potential of N-acetylcysteine (NAC) against mercury toxicity, specifically focusing on mercury accumulation and the expression of genes associated with oxidative stress and inflammation in the lung tissue of rats

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2022;283:114739 [Google Scholar] Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway

found that hypoxia reduces NCOA4 expression in human macrophages, and siRNA transfection experiments showed that knocking down NCOA4 increases FtMt expression, protecting macrophages from RSL3-induced ferroptosis [20]