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Taxol (paclitaxel) was first isolated in 1971 from the bark of Taxus brevifolia and was approved in 1992 by the US Food and Drug Administration for treatment of metastatic ovarian cancer and later for breast cancer

GPx1 is the predominant isoform of glutathione peroxidase

10.3389/fphar.2024.1348076 Summary Keywords natural compounds, apoptosis, nanodelivery systems, chemoresistance, ovarian cancer Citation Muttiah B and Abdullah NAH (2026) Natural compounds in ovarian cancer: mechanistic insights and therapeutic potential