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Abstract Obesity and type 2 diabetes mellitus (T2DM) are widespread, non-communicable diseases that are responsible for considerable levels of morbidity and mortality globally, primarily in the form of cardiovascular disease (CVD)

Mol Aspects Med 2018;62:75-88

Clinical Principle The IC/BPS diagnosis should be reconsidered if no improvement occurs after multiple treatment approaches

The results showed that compared with insulin glargine, Tirzepatide showed better HbA1c and weight reduction in the population of type 2 diabetes patients in the Asia-Pacific region (mainly China): HbA1c reduction of up to 2.49% and weight reduction of up to 7.2 kg (9.4%) at 40 weeks of treatment, significant improvement in blood lipids and blood pressure, and overall safety and tolerability were good