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Furthermore, acupuncture has been shown to significantly enhance lipid metabolism and the systemic inflammatory response in HFD-induced NAFLD rats, possibly through the regulation of the intestinal microbiota composition [169]

Their causal analysis identified that NMN was linked to the upregulation of TH17-derived cytokines, including IL-17a and IL-17f, which were associated with the activation of master regulators such as FBXW7 and Sirt3

Suppression of NOD-like receptor protein 3 inflammasome activation and macrophage M1 polarization by hederagenin contributes to attenuation of sepsis-induced acute lung injury in rats

This distinct microbial feature was intimately linked to the observed disturbances in epithelium barrier integrity and pro-inflammatory signaling in the intestine