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Female Kunming mice and BALB/c nude mice were used in this study

Whitfield-Cargile CM, et al

Continuous-flow microfluidic systems enable controlled nanoparticle assembly with improved batch uniformity and reduced solvent consumption, making them suitable for large-scale manufacturing compared to traditional batch methods [115]

Before birth, the OPCs proliferate and migrate throughout the CNS parenchyma, but myelination occurs principally during the postnatal period, when OPCs differentiate and become myelinating OLGs

More chronic, placebo-controlled human studies are required to evaluate not only the bioavailability and efficacy of various polyphenol formulations and delivery systems but also to establish standardized dosages, monitor potential side effects, and assess inter-individual differences in responses due to genetics and gut microbiota composition (126, 127)