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Description

A.Borromeo-AustinC.HebrokM

NAC treatment was an additional negative control

pH-sensitive targets The tumor microenvironment and intracellular compartments like endosomes and lysosomes often exhibit a lower pH, which can be exploited by pH-sensitive nanocomposites for targeted drug release [136]

No sterile water must be discarded immediately after opening, while bacteriostatic water can last longer if handled aseptically

As reported in Table 1, among the analyzed tumor types, CRC shows the highest number of preclinical studies on DNA methylation ( N = 24), including 16 diagnostic and eight prognostic studies