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they may be directly involved in the regulation of blood glucose (88) or indirectly involved through the gut-kidney axis, improving lipid metabolism to protect the kidney (89)

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Iron then circulates in the bloodstream, while surplus iron is stored in the liver as ferritin, which can be utilized when the demand arises

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It was not until 2012 that Stockwells team first described and coined the term ferroptosis for this a lethal program fueled by catalytic iron and driven by lipid peroxidation, which is marked via a surge in membrane-bound reactive oxygen radical (Dixon et al., 2012)

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For systemic administration of ozone, such as in major autohemotherapy (MAH), the concentration range should fall within 1040 g/mL, with 1020 g/mL of blood considered biologically relevant

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The Journals of Gerontology

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