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doi: 10.1161/ATVBAHA.111.226902

In line with the in vitro studies, paclitaxel-induced mitochondrial dysfunction significantly hampered cellular respiratory function and ATP production in DRG neurons (Duggett et al., 2017), leading to neuronal apoptosis (Chine et al., 2019a)

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344 In 54 patients with type 2 diabetes and mild-to-moderate combined depression and anxiety, mood symptoms and sleep improved more after taking 30 mg saffron extract daily for eight weeks compared with placebo