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Evidence (cabozantinib): A phase III, randomized, double blind, placebo-controlled study (COSMIC-311 [NCT03690388]) was conducted to evaluate the efficacy of cabozantinib in patients aged 16 years and older with RAI-refractory differentiated thyroid cancer

Additionally, synthetic SOD mimetics are under investigation to replicate or improve the enzymes antioxidant activity while minimizing toxicity and immune responses