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Description

17 There is an 8.8% overall complication with this surgical approach

Sometimes, bone marrow transplantation is considered

Impaired Bone Marrow Function B12 deficiency also harms bone marrow function

Common adult research-context starting guidance is 100-200 mcg subQ at bedtime for the first 1-2 weeks, then titrating to 200-300 mcg nightly

There is around a 2.5-fold increase in B12 deficiency incidence in those treated with metformin, and this may occur as early as 3 months, although hepatic stores of vitamin B12 may take 5 years or more to deplete (Bell, 2022)