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Sustained cysteine supply via SLC7A11 maintains high intracellular GSH levels, which are required to support the catalytic activity of downstream effectors, such as GPX4

and protection of the skin from free radical inflammation, including sun exposure

doi: 10.1016/j.sciaf.2020.e00507 279 BarfootKLIstasGFelicianoRPLamportDJRiddellPRodriguez-MateosAet al

Although rare with topical scalp applications, the presence of hormones may result in systemic absorption, potentially causing mood changes, altered libido, or other hormone-related effects