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This interaction both disrupts peptidoglycan assembly in spore-forming bacilli and promotes the aggregation of nisinlipid complexes that create pores in the cytoplasmic membrane, leading to loss of membrane integrity and cell death (198, 199)

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Increased oxidative stress caused by environmental toxins, UV radiation or physical and mental stress increases the body's consumption of glutathione

Single-cell RNA sequencing analyses have revealed distinct ferroptosis signatures in CD patients [83]