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This may be related to the reduction of butyric acid-producing members of clostridial cluster, such as Clostridium coccoides and Clostridium leptum , and the abundance of Fecalibacterium prausnitzii and Roseburia intestinalis was significantly associated with severe of UC [149, 150]

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19 ) and MTARC1 (ref

The Omicron variant was associated with sleep deterioration (new onset insomnia or exacerbation of chronic insomnia) together with altered brain structures in infected patients compared to healthy never-infected controls [234]