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Rightmost panel: Influence of CSE overexpression (OE) on the viability of U2OS cells treated for 24 h with either RSL3 (5 M) or CHP (40 M), as measured with an ATP assay

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Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp

Together these data support the proposed mechanism that dihexa facilitates dimerization of HGF that subsequently activates the MET receptor and, subsequently, downstream intracellular signaling pathways 22