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Hypoglycemia with insulin or insulin secretagogues

Interestingly, induction of c-MET phosphorylation was observed upon the blockade of PI3K/AKT signaling, confirming a negative control of c-MET activity by AKT and warranting clinical investigation to determine the significance of p-c-MET as an escape mechanism to AKT inhibitors (Fig

New England Journal of Medicine, 384(8), 727743

This makes them not only an already optimal solution for TD-DCS in laboratory settings for exploitative measurement campaigns, but also a dynamic field of research with potential to develop soon breakthrough technologies capable of revolutionizing the clinical environment 49