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An integrative use of in vitro BBB models and in vivo techniques, together with advances in medicinal chemistry and tailor-made design of antibodies, proteins and peptides, are likely to be of key importance

and T.M.), Tohoku University-AIST Joint program (to L.S

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These proinflammatory changes were shown to increase the binding of fluorescently-labeled leukocytes to the GPx1-deficient endothelial cells compared to the wildtype cells [85]