foxo4-dri senolytic or senomorphic Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells ScienceDirect FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect Targeting Cellular Senescence in Aging and Age Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies Senolytics: charting a new course or enhancing existing anti tumor therapies? Cellular Oncology Springer Nature Link
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