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All patients maintained concomitant NA therapy throughout the study, resulting in low/undetectable RNA/DNA and a high proportion of undetermined genotypes (51%, 28/55 for Arm 1

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In addition, unique to c-MET is its association with the adaptor protein GRB2-associated binding protein 1 (GAB1) [Weidner et al

While targeted biochemical analysis reveals direct mediators of specific substrate interactions within a complex, combining these analyses with affinity measurements in the context of multimeric assemblies in complex lysates takes into consideration the possibility of larger molecular regulatory networks