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Despite the initial shift toward glycolysis, microglia in advanced stages of Alzheimer's disease experience a decline in both glycolytic and oxidative phosphorylation pathways, resulting in a state of energetic exhaustion that impairs their ability to clear debris and protect neurons (103)

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These findings do not establish Epithalon as a human longevity, sleep, anti-ageing or disease treatment

Aging (Albany NY) 13(7):9582 Gao X, Wang B, Huang Y, Wu M, Li Y, Li Y, Zhu X, Wu M (2023) Role of the Nrf2 signaling pathway in ovarian aging: potential mechanism and protective strategies

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