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Quintero-Monzon O, Martin MM, Fernandez MA, Cappello CA, Krzysiak AJ, Osenkowski P, et al

The intracellular imbalance between oxidant and antioxidant due to the abnormal expression of multiple redox active enzymes will promote the produce of reactive oxygen species (ROS)

This suggests that in the presence of APAP overdose the concentration of glutamate may also be rate-limiting for the regeneration of GSH

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

[DOI] [PubMed] [Google Scholar] Ceriello A, Quagliaro L, Catone B, Pascon R, Piazzola M, Bais B, Marra G, Tonutti L, Taboga C, Motz E