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This work was supported by a grant PID2019-104690RB-I00 funded by MCIN/AEI/ 10.13039/501100011033 to J.G.-A

Allergic reactions : Some people may be allergic to one or more of the ingredients in B complex supplements, such as cobalt or other additives

It was shown that BRCA1 occupied the NNMT promoter and regulating its expression ( BRCA1 and CDK12 depletion contribute to mitochondrial respiration defects and decreased ATP levels due to the reduced mitochondrial DNA copy number rather than mitochondrial number, which suggest that they stem from decreased flux through electron transport complexes rather than a decrease in mitochondria (66)

This means that there is zero chance of allergic reaction

Understanding nutrients like B12 helps you make confident choices that support your energy, brain health, and long-term wellbeing Both methylcobalamin and cyanocobalamin can help maintain healthy B12 levels and the most important thing to remember is consistency regardless of where that B12 comes from