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A master transcription factor in the regulation of glycolysis is hypoxia-inducible factor 1 (HIF-1) because it promotes the transcription of glucose transporters, such as glucose transporter 1 (GLUT1), and glycolytic enzymes, such as hexokinase II (HK-II), and pyruvate kinase M2 (PKM2) (Yu et al., 2017)

Discussion The observed lower proportional reporting of infections associated with belimumab compared to TNF inhibitors is a notable finding of our analysis

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