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The effects of sex hormones on immune function: a meta-analysis

A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vision

Hanaford A, Johnson SC (2022) The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence

There are a couple of different types of white spots that can occur from sun exposure (although, as we mentioned, the exact cause isn't entirely known)

Intact p53 is required for interphase apoptosis (Fridman and Lowe, 2003), while disruptive TP53 mutations are associated with increased radioresistance via the inhibition of senescence (Skinner et al., 2012)