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Reasons why mitochondria might be impaired or damaged include: Aging Inadequate diet Poor sleep Lack of exercise Genetics Heavy and toxic metals Pollutants Free radicals Prescription drugs Alcohol There are many conditions that are caused or made worse by mitochondrial dysfunction, such as the following per Pizzorno (2014): Early aging Amyotrophic lateral sclerosis Alzheimers disease Autism Cardiovascular disease Chronic fatigue syndrome Dementia Diabetes Huntingtons disease Migraine headache Parkinsons disease A great way to directly influence the health of our mitochondria is through the use of peptides

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Phenylethanoid and lignan glycosides from Verbascum thapsus

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[6] Blood tests may show fewer but larger red blood cells, low numbers of young red blood cells, low levels of vitamin B 12 , and antibodies to intrinsic factor