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Some people with certain deficiencies such as Crohns disease and coeliac may struggle to get enough B12 in their diet. If you think youve overdosed on vitamin B12, Dr Thornber recommends you contact your GP or a hospital ASAP.

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The capacity of AML cells to detoxify lipid peroxides by increasing their cystine uptake to maintain major antioxidant molecule glutathione biosynthesis after exposure to APR-246 may be a key determinant of sensitivity to this compound