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In our group, we have demonstrated that low doses of IGF-I restored circulating IGF-I levels, which improves insulin resistance and lipid metabolism in aging rats[55], thus becoming a potential beneficial agent to prevent insulin resistance-related pathologies

Intranasal delivery, used with Selank and Semax, bypasses first-pass enzymatic metabolism in some systems, which partially explains why researchers observe longer effective durations than the IV values listed in typical half-life reference data

The I-kappaB kinase (IKK) family activates NF-B, which then translocates to the nucleus, where it promotes gene expression

Growth hormone acts along the PPAR-FSP27 axis to stimulate lipolysis in human adipocytes

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