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These two receptors can, moreover, form heterodimers, which bind both ligands

Researchers designed Adipotide to target the vasculature supporting white adipose tissue rather than the fat cells themselves

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Their anti-tumor activity depends on Fc-dependent immune effector mechanisms and immunomodulatory effects that eliminate CD38 regulatory T cells and restore T-cell- and NK-cell-mediated antitumor immune responses [56]