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In addition to inhibiting NF-B, riboflavin inhibits the release and expression of High-mobility group protein B1, a nuclear factor involved in sepsis regulation and other immune-mediated conditions with a critical role in sepsis-associated multiple organ failure (60)

That led us to wonder whether a compound with strong antioxidant capacity might protect HGF, either by preventing nitration or by compensating for the functional loss it causes. The team turned to two sulfur-based compounds known for strong antioxidant activity: glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS)

Quantitative Analysis of Platelet Surface HLA by W6/32 Anti-HLA Monoclonal Antibody

The study by Sha et al., 2021)

4 To prevent such damage, cells maintain redox homeostasis through an elaborate antioxidant defense system (Fig