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3rd International Symposium on 3D Radiation Treatment Planning and Conformal Therapy

435 Sirolimus has also shown efficacy in rare diseases such as lymphangioleiomyomatosis (NCT00414648) and renal angiomyolipoma in tuberous sclerosis complex (TSC) (NCT00457808), 436,437 where mTOR-driven cell proliferation and dysregulated autophagy are key features

We propose patients who pause treatment may have testing repeated after 2 weeks, while those with resolving aminotransferase elevations may reinitiate omaveloxolone with stepwise dose titrations and testing every 2 weeks for 3 months

These data provided validation of ACS as a potential antifungal drug target

Table 1 Interaction of arsenic with nutrients and its implication on plant and human health