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doi: 10.1007/s12015-021-10147-5 156 Del PiccoloNShirureVSBiYGoedegebuureSPGholamiSHughesCCWet al

The addition of CB-839 to temozolomide significantly reduces glioma aspartate and glutamate in an IDH mutated patient derived glioma xenograft model

The need for long-term data collection for a gene therapy trial can last up to 15 yearsanother reason to consider all outcomes and responsibilities that come with committing to a clinical trial

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The levels of glutathione depend on the mutation in question, and nrc1 , cad2-1 , pad2-1 and zir1 , which are affected in GSH1 show glutathione levels that range from 45 to 15% of normal levels 50,51,54,68