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November 15 Product: Revuforj Indication: Relapsed or refractory acute leukemia with a lysine methyltransferase 2A gene translocation Syndax Pharmaceuticals Revuforj (revumenib) on Friday became the markets first menin inhibitor for relapsed or refractory acute leukemia when the FDA cleared it for use in adult or pediatric patients carrying a translocation mutation in the lysine methyltransferase 2A ( KMT2A ) gene