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doi: 10.1016/j.jddst.2024.106550

TME-based studies could increase treatment efficacy, addressing nonspecificity and resistance

Each term was represented by a circle node, its size was proportional to the number of input genes in that term and its color represented cluster identity

Arginase Bypass - L-citrulline isn't affected by the enzyme arginase , which breaks down L-arginine in the gut and liver

Notably, these potent GST P1-1 inhibitors display equivalent activity against the more invasive MDA-MB-231 cell line that expresses GST P1-1 compared with the MCF-7 cell line