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During the inflammatory process, the activation of immune cells such as neutrophils not only further triggers the accumulation of cholesterol and calcium crystals but may also damage gallbladder endothelial cells, affecting normal gallbladder function, such as reduced bile emptying capacity, thus exacerbating bile stasis and forming a vicious cycle (24, 25)

[DOI] [PMC free article] [PubMed] [Google Scholar] Sausen de Freitas A, de Souza Prestes A, Wagner C, Haigert Sudati Js, Alves D, Oliveira Porcincula L, Kade IJ, Teixeira Rocha JoB