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Nevertheless, findings have indicated that the presence of certain activating receptors, or combinations of coactivating receptors, on NK cell surface can potentiate NK effector function in MHC-I positive tumors [187,188,189,190]

The largest double-blind, randomized, controlled trial (RCT) to date ( n = 147) used 2 treatment sessions with a 6-month follow-up, and demonstrated that PMMA provided a statistically significant superior treatment for atrophic facial acne scarring of 64%, versus 33% in the control arm ( P = 0.0005)