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The project was directed by MR and HFN who also wrote the manuscript

Acute coronary syndromes: mechanisms, challenges, and new opportunities

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O 2 further undergoes dismutation reaction catalyzed by SOD or O 2 can be reduced by PQH 2 (see above), to produce H 2 O 2 , which in turn is reduced by Asc with the involvement of ascorbate peroxidase (APX), generating H 2 O and monodehydroascorbate radical (MDHA) (Figure 5)