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doi: 10.1016/j.phymed.2017.04.005, 63

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(2) Gastrointestinal GPx (GPx2) is only found in the cytosol and nucleus of the gastrointestinal tract

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Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: evidence for a role in hepcidin induction by inflammation in male mice

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Consistently, HIF1A also promotes GSH synthesis through transcriptional activation of GCLM and SLC7A11 , and pharmacological inhibition of SLC7A11 with erastin or sorafenib exacerbates cuproptosis 177,178

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Surprisingly, we still detected an induction effect of DMF on most of the factors studied despite NRF2 silencing (Fig

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