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Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra

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Therefore, there are multiple factors to consider when outlining the biggest differences between the two melanocortin agonists: Molecular Structure: While both MT1 and MT2 are synthetic analogs of alpha-MSH, they have only four amino acids in common: the sequence His-D-Phe-Arg-Trp (positions three to six in MT2)