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To this aim, we segregated the cohort of 147 patients with lung cancer according to the median histidine intake normalized to total calorie intake (1.25 grams per 1,000 kcal per day), revealing in univariable and multivariable Cox logistic regression analysis that histidine consumption 1.25 g per 1,000 kcal per day was associated with prolonged PFS (hazard ratio (HR) 0.64 (0.430.96)

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doi: 10.1159/000369822, 108 YamadaS.TanakaS.SekiS.KogoM

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It helps maintain the tablets stability throughout its shelf life