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Heat stress decreases testicular germ cell proliferation and increases apoptosis in short term: an immunohistochemical and ultrastructural study

GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways

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[ 88 , 94 , 472 , 474 , 475 ] Keap1, the most validated target for NRF2 activation, is a redox sensor containing several cysteine residues, whose oxidation or modification compromises either dimeric structure formation or combination to ubiquitin ligase, resulting in NRF2 protein release and nuclear import