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Overall, the elongated ASXL1 EBM -binding groove, delineated by I622, L630, V633, V634, I652, I654 and F656 of BRD4 ET , is mainly hydrophobic but is surrounded by the negatively charged walls created by the residues of the 1 strand and the 2-3 loop of BRD4 ET , such as D650, E651, E653, D655 and E657 (Fig

In contrast, GSSG is less susceptible to decomposition in aqueous solution and is suitable for use in liquid form, although the skin-whitening effect of topical GSSG is unknown

Bonferroni-Dunn correction for multiple comparisons was included in statistical analyses performed in c and d

J Nanobiotechnol 21(1):452 Yang Z et al (2021) The transcription factors CREBH, PPARa, and FOXO1 as critical hepatic mediators of diet-induced metabolic dysregulation

Still, the practice of using glutathione for skin whitening persists, with IV glutathione being administered locally and shipped internationally