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From a translational perspective, factors such as anatomical differences between murine and human rectal structures, inter-individual variability in suppository retention, and formulation scale-up may influence clinical applicability

The animal was left in the cage for 5 min (adaptation period) before being connected to the ECoG recording setup via a commutator that allows its movement during signal recording

Higher MDA levels are directly associated with oxidative stress, which heightens the susceptibility of periparturient dairy cattle to mastitis

However, investigation of the effect of UA on such models is limited by the profound differences between humans and e.g., rodents in UA metabolism, primarily due to the loss in humans of a functional uricase

LECs III are characterized by the expression of microfibril associated protein 4 (MFAP4) and LYVE1