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Jpn J Pharmacol 89(1):720

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Khaksar V, Hervo F, Mme N, Monteiro AR, Narcy A

Reduced mitochondrial DNA copy number in Chinese patients with osteosarcoma

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MOTS-c was found to upregulate key genes in the TGF-/Smad pathway (such as TGF-1, TGF-2, and Smad7) and increase the expression of bone formation markers like alkaline phosphatase (ALP), osteocalcin, and Runx2 in bone cells