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10.1016/j.spinee.2009.10.018 37 KirnazS.CapadonaC.WongT.GoldbergJ

In this study, all early and late phase markers of odonto/osteogenic differentiation were highly expressed in IGF-1-treated SCAPs with the low-expression of hsa-let-7c , but significantly downregulated in Let-7c overexpression group, indicating that hsa-let-7c was paramount to the IGF-1/IGF-1R/ hsa-let-7c axis