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Consumption of a Mediterranean diet (MedDiet) has been demonstrated to reduce risk of various non-communicable diseases and increase longevity

Thus, glutamine by selectively increasing tumor retention of MTX compared with normal host tissue increases the therapeutic window of chemotherapeutic drugs.[75] Experimental evidence indicates a very good correlation between the activity of mitochondrial GA and the rate of respiration of tumor mitochondria in the presence of glutamine.[78] ROLE OF GLUTAMINE IN METABOLISM-DEPENDENT TOXICITY OF CYCLOPHOSPHAMIDE Studies have shown that acrolein produced during the metabolism of cyclophosphamide (CP) binds to proteins and, by doing so, may denature these proteins and acrolein in vivo, preferentially reacting with GSH and sulfhydryl-containing compounds, and may protect against acrolein toxicity and at the same time not interfere with the chemotherapeutic activity of CP.[79] The main source of this GSH is glutamine

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While these products can provide localized benefits, they may not offer the same systemic effects as oral or IV options

Fuhlbrigge, Tracy Andrews, and CARRA Registry Investigators Initial Validation of IBD KNOW-IT: Measuring Patient and Caregiver Knowledge of a Child's Disease and Treatment Regimen., Michele H