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Baolin Qu, [email protected] These authors have contributed equally to this work This article was submitted to Molecular Diagnostics and Therapeutics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Shelf life: 24 Months

Long-term recovery extends beyond six months, with potential for significant neurological improvement if youve received early intervention

Based on the initial finding that FXa-resistant PAR2-G37I mice are protected from obesity, we have systematically interrogated PAR2-activating roles of FX expressed by innate immune cells or IECs