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doi: 10.1016/j.cell.2012.05.003 10 PanYMaPLiuYLiWShuY

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Cao, H., Duan, L., Zhang, Y., Cao, J

It is usually the first ROS to be formed

However, increasing non-ionic surfactants and cholesterol beyond optimal levels (above 30 mg) led to reduced entrapment efficiency and larger particle sizes in niosomes, likely due to disrupted vesicular structures and potential formation of mixed micelles 56,57