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On the other hand, endoplasmic reticulum stress can promote cell ferroptosis and may be involved in the co-regulation of ferroptosis and apoptosis [61]

Some researchers may require higher doses or longer cycles to achieve noticeable effects, though increasing beyond standard protocols should be approached cautiously

It is not appropriate during pregnancy or breastfeeding, in active cancer, or in patients with severely uncontrolled metabolic disease without specialist coordination

Sample preparation for UHPLC-MS/MS The methanol (1.2 mL) containing the IS solution (10 g/mL, GSH- 13 C 2 , 15 N for negative ion mode (Neg)) was added to the cell-cultured plate and maintained for 2 min

Khallaf et al