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When attempting to diagnose either candidemia or biofilm infections and determine the severity of the infection, physicians primarily rely on laboratory cultures, molecular assays, and serum tests (e.g., -D-glucan or mannan/anti-mannan), which indicate the total fungal burden but do not necessarily correlate with the existence of persistence-related reservoirs

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HaloTag protein tag is a 34kDa, monomeric protein tag modified from Rhodococcus rhodochrous dehalogenase